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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
E2F1
All Species:
6.67
Human Site:
T196
Identified Species:
12.22
UniProt:
Q01094
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q01094
NP_005216.1
437
46920
T196
Q
W
L
G
S
H
T
T
V
G
V
G
G
R
L
Chimpanzee
Pan troglodytes
XP_524538
437
47536
D200
V
G
R
G
M
F
E
D
P
T
R
P
G
K
Q
Rhesus Macaque
Macaca mulatta
XP_001103717
502
53768
T261
Q
W
L
G
S
H
T
T
V
G
V
S
G
R
L
Dog
Lupus familis
XP_542963
571
61192
A331
Q
W
L
G
S
H
A
A
V
G
I
S
G
R
L
Cat
Felis silvestris
Mouse
Mus musculus
Q61501
430
46305
M191
Q
W
L
G
S
H
T
M
V
G
I
G
K
R
L
Rat
Rattus norvegicus
Q62814
300
33206
K70
S
K
N
S
I
Q
W
K
G
V
G
A
G
C
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515449
468
50133
A208
G
V
L
D
L
N
R
A
A
E
V
L
E
V
Q
Chicken
Gallus gallus
Q90977
403
43534
A173
Q
W
L
G
S
Q
V
A
A
G
A
S
S
R
Q
Frog
Xenopus laevis
NP_001090608
426
47125
S188
Q
W
L
G
Y
T
S
S
V
E
F
S
S
R
Y
Zebra Danio
Brachydanio rerio
NP_001074097
429
46452
P199
Q
W
L
G
S
S
L
P
S
D
G
G
L
P
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27368
805
87442
M323
Q
W
R
C
G
Q
S
M
V
S
Q
E
R
S
R
Honey Bee
Apis mellifera
XP_396223
416
46049
I186
N
V
L
E
G
I
G
I
L
E
K
K
S
K
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001123287
404
44387
D173
V
Q
K
R
R
I
Y
D
I
T
N
V
L
E
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40.7
86
70.9
N.A.
84.6
23.1
N.A.
39.9
59.9
49.8
37.2
N.A.
20.6
29.7
N.A.
38.4
Protein Similarity:
100
54.4
86.2
72.6
N.A.
88.5
37.9
N.A.
51.2
70
63.3
53.7
N.A.
31.5
46.4
N.A.
54.2
P-Site Identity:
100
13.3
93.3
73.3
N.A.
80
6.6
N.A.
13.3
46.6
40
40
N.A.
20
6.6
N.A.
0
P-Site Similarity:
100
20
93.3
80
N.A.
86.6
6.6
N.A.
20
46.6
53.3
40
N.A.
26.6
20
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
24
16
0
8
8
0
0
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
0
8
0
0
0
16
0
8
0
0
0
0
0
% D
% Glu:
0
0
0
8
0
0
8
0
0
24
0
8
8
8
0
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
8
0
0
0
0
% F
% Gly:
8
8
0
62
16
0
8
0
8
39
16
24
39
0
8
% G
% His:
0
0
0
0
0
31
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
16
0
8
8
0
16
0
0
0
0
% I
% Lys:
0
8
8
0
0
0
0
8
0
0
8
8
8
16
0
% K
% Leu:
0
0
70
0
8
0
8
0
8
0
0
8
16
0
31
% L
% Met:
0
0
0
0
8
0
0
16
0
0
0
0
0
0
0
% M
% Asn:
8
0
8
0
0
8
0
0
0
0
8
0
0
0
16
% N
% Pro:
0
0
0
0
0
0
0
8
8
0
0
8
0
8
0
% P
% Gln:
62
8
0
0
0
24
0
0
0
0
8
0
0
0
24
% Q
% Arg:
0
0
16
8
8
0
8
0
0
0
8
0
8
47
8
% R
% Ser:
8
0
0
8
47
8
16
8
8
8
0
31
24
8
8
% S
% Thr:
0
0
0
0
0
8
24
16
0
16
0
0
0
0
0
% T
% Val:
16
16
0
0
0
0
8
0
47
8
24
8
0
8
0
% V
% Trp:
0
62
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _